Genomics for Animal Health: Outlook for the Future
12th - 15th October 2009
Muséum National d'Histoire Naturelle, Paris, France
The fifth and final EADGENE annual conference on Animal Genomics Research took place on 12th - 15th October 2009, at the Muséum National d'Histoire Naturelle, Paris, France. This venue was particularly appropriate for an animal genomics conference as 2009 was the 200th anniversary of Charles Darwin’s birth, and it was also the 150th anniversary of the publication of his enormously influential book, "On the Origin of Species."
The main 2-day conference featured a series of talks on the latest genetics and genomics research and technologies by keynote speakers and leading specialists in their fields, presentations on the results of the EADGENE project, and there was a particular emphasis on the future of animal health genomics. The conference was preceded by a 1-day satellite workshop on Bioinformatics and Data Handling for Next Generation Sequencing, and followed by two 1-day satellite workshops on Mastitis and on Animal Health Data Comparison.
Monday 12th October
Tuesday 13th October
Please click on titles to download PDF versions of the presentations. More presentations will be added as we obtain permission to publish from speakers.
Session 1: Technologies and Approaches
Chair: John Williams (PTP, Italy)
- Welcome - Marie-Hélène Pinard van der Laan (EADGENE Co-ordinator, INRA, France)
- Next generation sequencing technologies and bacterial genomics - Nicholas Thomson (Wellcome Trust Sanger Institute, UK)
- Assessing the effect of the CLPG mutation on the microRNA catalogue of skeletal muscle using high throughput sequencing … possible contribution to polar overdominance - Michel Georges (University of Liege, Belgium)
- Genetic-epidemiological models - Johann Detilleux (University of Liege, Belgium)
- Approaches to filling that "phenotype gap" - Liz Glass (Roslin Institute and R(D)SVS, University of Edinburgh, UK)
- Post-analyses of microarray data - Florence Jaffrezic (INRA, France)
- Microarray quality control exchange experiment - Jakob Hedegaard (University of Aarhus, Denmark)
- Systems biology in animal science - Henri Woelders (ASG Lelystad, Wageningen UR, The Netherlands)
Session 2: Research Results
Chair: Madeleine Douaire (INRA, France)
- Population genetics and disease genetics - Dan Bradley (Trinity College Dublin, Ireland) - This presentation is not available for download
- QTL mapping applied to disease resistance in salmon - Thomas Moen (AquaGen, Norway)
- Gene expression profiling in divergent lines of sheep for enhanced insight into genetic resistance to mastitis - Rachel Rupp (INRA, France)
- EADGENE’s technology transfer poultry projects:
- Facilitating ethical reflection among scientists: Using the ethical matrix as a tool - Karsten Klint Jensen (Danish Centre for Bioethics and Risk Assessment (CeBRA), Denmark)
- Results of short-term stays at other partners:
- Submitted short communications (5 minutes per presentation):
- Current progress of the US PRRS Host Genetics Consortium - Joan Lunney (USDA ARS BARC APDL, USA)
- Gene expression analysis in the jejunum of pigs responding differently to a challenge with enteric bacterial pathogens - Marcel Hulst (ASG Lelystad, Wageningen UR, The Netherlands) - This presentation is not available for download
- Macrophages and dendritic cells have distinct transcriptome profiles during early infection with Salmonella Typhimurium - Anna Kaliszewska (Roslin Institute and R(D)SVS, University of Edinburgh, UK)
- Chicken macrophage transcriptional response to TLR pathway stimulants - Susan Lamont (Iowa State University, USA)
- The Systome: Tools to enable systems biology for veterinary genomics - Michael Watson (Institute for Animal Health, UK)
- Inferring gene regulatory networks from gene expression time series data - Dirkjan Schokker (ASG Lelystad, Wageningen UR, The Netherlands)
- Are gene networks always meaningful? - Magali San Cristobal (INRA, France)
- Using transcriptomics to develop predictive tools for identifying pigs with superior immune response and improved food safety - Christopher Tuggle (Iowa State University, USA)
Evening Events: Delegates were invited to explore the displays in the Galerie de l’évolution, followed by a conference cocktail session and buffet in the Galerie de l’évolution.
Wednesday 14th October
Session 3: Focus on Pathogens
Chair: Fiona Tomley (Institute for Animal Health, UK)
- Pathogen genomics: approaches and applications - Vega Masignani (Novartis, Italy)
- Genetic analysis of Salmonella & E. coli pathogenesis in farm animals - Mark Stevens (Institute for Animal Health, UK)
- Emerging and re-emerging viruses - John Fazakerley (Roslin Institute and R(D)SVS, University of Edinburgh, UK)
- EADGENE’s fish pathogen research - Espen Rimstad (NSVS, Norway)
- Role of TLR4, and TLR4-dependent signalling pathways, in the resistance to Salmonella infection and carrier state - Philippe Velge (INRA, France)
- Streptococcus suis: genome based approaches to identify virulence factors and vaccine candidates - Hilde Smith (ASG Lelystad, Wageningen UR, The Netherlands)
- Development of in vivo mastitis models - Wolfram Petzl (LMU Munich, Germany)
Session 4: Breeding to improve animal health
Chair: Alan Archibald (Roslin Institute and R(D)SVS, University of Edinburgh, UK)
Conference closing speech
Thursday 15th October